Yesterday I officially moved up from the $3 45s to the $6 45s. Not a real big jump in skill level it turns out, since the majority of players are still really bad. Moving up is always a psychological thing. As long as you have the bankroll and are comfortable with risking slightly more you will be ok. I have well over 100 buyins for the games i play.
I played 5 $6/45 tournies and monied 3. One 1st, a 2nd and 6th place finish. for a whopping 500% ROI. I also played 2 $4/180s and 2 $3/45 but did not money in any.